The data underlying Figs 3 and S5.

(A) Results from sphingolipidomic analyses demonstrating alterations induced by the cpoS mutant. HeLa cells were infected with the indicated strains and lipid extracts were prepared at 14 hpi. Data are displayed in Figs 3A and S5. (B) Results from sphingolipidomic analyses testing the effect of SKI-II. Lipid extracts were prepared 14 hrs post infection and treatment. Data are displayed in Fig 3B. (C) SKI-II induced death in cells infected with CTL2. Host cell viability based on resorufin fluorescence measured 25.5 hrs post treatment with SKI-II and infection with the indicated bacterial strains. Data are displayed in Fig 3C. (D) SKI-II induced death in cells infected with CTL2 at concentrations non-toxic to uninfected cells. Host cell viability based on resorufin fluorescence measured 34 hrs post infection and treatment with the indicated concentrations of SKI-II. Data are displayed in Fig 3D. (XLSX)