首页/数据集/CRISPR/Cas9 Screen Reveals PRKCB-Mediated Phosphorylation of YBX1 Promotes Oxaliplatin Resistance in Colorectal Cancer

CRISPR/Cas9 Screen Reveals PRKCB-Mediated Phosphorylation of YBX1 Promotes Oxaliplatin Resistance in Colorectal Cancer

Name: CRISPR/Cas9 Screen Reveals PRKCB-Mediated Phosphorylation of YBX1 Promotes Oxaliplatin Resistance in Colorectal Cancer
Creator: Zhejiang University
Published: 2025-12-29T20:38:13+08:00

integrated proteome resources2026-07-03 收录

化疗耐药机制

功能基因组筛选

数据链接：

https://www.iprox.cn/page/project.html?id=IPX0014913000 数据链接链接失效反馈

官方服务：

资源简介：

CRISPR/Cas9 Screen Reveals PRKCB-Mediated Phosphorylation of YBX1 Promotes Oxaliplatin Resistance in Colorectal Cancer

应用场景：

提供机构：

Zhejiang University

创建时间：

2025-12-29

头颈部鳞状细胞癌基因

化疗耐药机制

In order to investigate the mechanisms underlying response and resistance towards treatment in HNSCC, we used low passage in vitro HNSCC cultures from two patients, namely SJG26 and SJG17. Both cultur

NIAID Data Ecosystem70

Data sheet index below 1.

功能基因组筛选

肿瘤代谢

In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a

Figshare2022-09-22 更新50

DataSheet9_Therapeutic Suppression of FAK-AKT Signaling Overcomes Resistance to SHP2 Inhibition in Colorectal Carcinoma.ZIP

化疗耐药机制

AKT信号通路

SHP2 mediates signaling from multiple receptor tyrosine kinases (RTKs) to extracellular signal-regulated kinase (ERK) and Ser and Thr kinase AKT, and its inhibitors offer an unprecedented opportunity

NIAID Data Ecosystem10

Integrative Analyses of Gene Expression and DNA Methylation Profiles in a Breast Cancer Cell Line Model of Tamoxifen-Resistance Indicate a Crucial Role of Cells with Stem-like Properties. Homo sapiens

化疗耐药机制

表观遗传调控

Purpose: Development of resistance to tamoxifen is an important clinical issue in the treatment of patients with breast cancer. Tamoxifen resistance may be the result of the acquisition of epigenetic

NIAID Data Ecosystem50

Loss of IFN-g signaling in tumor cells associates with primary resistance to anti-CTLA-4 therapy

化疗耐药机制

IFN-γ信号通路

"Antibody blockade of the inhibitory CTLA-4 pathway has led to clinical benefit in a subset of patients with metastatic melanoma. Anti-CTLA-4 enhances T cell responses, including production of IFN-?,

NIAID Data Ecosystem40

CRISPR/Cas9 Screen Reveals PRKCB-Mediated Phosphorylation of YBX1 Promotes Oxaliplatin Resistance in Colorectal Cancer

资源简介：

相关数据集