A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation. Homo sapiens

A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. We report the identification and biologic characterization of an LPS-like molecule extracted from the cyanobacterium Oscillatoria Planktothrix FP1 (CyP). Keywords: different ligands Overall design: 2 untreated (CTR), 2 treated with LPS at 3h, 2 treated with CyP at 1h, 2 treated with CyP at 3h, 2 treated with LPS + CyP at 3h