Methods of development and utilization or randomized evidence in guidelines for advanced gynecological malignancies.

*the reference sources for the assignment of levels of evidence are as follows:(1)http://www.cancer.gov/cancertopics/pdq/levels-evidence-adult-treatment/HealthProfessional/page2;(2)Scottish Intercollegiate Guidelines Network. Methodology Review Group. Report on the review of the method of grading guideline recommendations. Edinburgh: SIGN; 1999.;(3)Cook DL, Guyatt GH, Laupacis A, et al: Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest 102:305S–311S, 1992 (suppl 4);(4)National Health and Medical Research Council (NHMRC). How to Use the Evidence: Assessment and Application of Scientific Evidence. Canberra, Australia: NHMRC; 2000;(5)http://www.uspreventiveservicestaskforce.org/uspstf08/methods/procmanual4.htm;(6)FIGO guidelines present a grading system for level of evidence (A–D) without specifying which system used.