Structure of human TRPA1 in complex with antagonist compound 21
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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Structure of human TRPA1 in complex with antagonist compound 21 Descriptor: 1-({3-[(3R,5R)-5-(4-fluorophenyl)oxolan-3-yl]-1,2,4-oxadiazol-5-yl}methyl)-7-methyl-1,7-dihydro-6H-purin-6-one, Transient receptor potential cation channel subfamily A member 1 Authors: Rohou, A, Rouge, L. Deposit date: 2020-08-20 Release date: 2021-03-31 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. J.Med.Chem., 64, 2021
创建时间:
2020-08-20



