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Bufospirostenin A and Bufogargarizin C, Steroids with Rearranged Skeletons from the Toad <i>Bufo bufo gargarizans</i>

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NIAID Data Ecosystem2026-03-10 收录
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Bufospirostenin A (1) and bufogargarizin C (2), two novel steroids with rearranged A/B rings, were isolated from the toad Bufo bufo gargarizans. Compound 1 represents the first spirostanol found in animals. Compound 2 is an unusual bufadienolide with a cycloheptatriene B ring. Their structures were elucidated by spectroscopic analysis, single crystal X-ray diffraction analysis, and computational calculations.

创建时间:
2017-03-02
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