Our study showed that chromosome 1 gene mutations occur frequently in 1p-intact neuroblastoma, but these do not consistently abrogate the function of bonafide tumor suppressors residing on 1p.. Mutational Analysis of 1p Tumor Suppressors in 1p-intact Neuroblastoma

肿瘤抑制基因

Deletion of 1p is associated with poor prognosis in neuroblastoma, however selected 1p-intact patients still experience poor outcomes. Since mutations of 1p genes may produce deleterious functional ef

NIAID Data Ecosystem120

Transcription profiling of transfected A549 lung cancer cell line with new tumor supressor gen ARLTS1 in that shows a very low expression level in comparison with normal lung

肿瘤抑制基因

癌细胞转录组

We have transfected a new tumor suppresor gene named ARLTS1 in A549 lung cancer cell line that shows a very low expression level in comparison with normal lung. This line was transfected using the pMV

NIAID Data Ecosystem50

Impact of short- and long-term extracellular acidosis on gene expression of tumors in vitro and in vivo

肿瘤微环境酸性

癌细胞基因表达

Purpose: The aim of the study was to analyze the impact of acidic pHe on gene expression in two experimental tumor lines of the rat in vitro and in vivo. The results of short-term incubation (24 h) we

NIAID Data Ecosystem50

Transcription profiling of transfected A549 lung cancer cell line with new tumor supressor gen ARLTS1 in that shows a very low expression level in comparison with normal lung

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