Human IgG1 lacking complement-dependent cytotoxicity: hu3S193 Fc mutant K322A
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Human IgG1 lacking complement-dependent cytotoxicity: hu3S193 Fc mutant K322A Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Farrugia, W, Burvenich, I.G.J, Scott, A.M, Ramsland, P.A. Deposit date: 2017-12-22 Release date: 2018-06-13 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions. Biochem. J., 475, 2018
创建时间：
2017-12-22
