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In-depth proteomic analysis of mouse microglia using a combination of FASP and StageTip-based, high pH, reversed-phase fractionation.

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https://www.omicsdi.org/dataset/gpmdb/GPM11210021378
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资源简介:
Data from ProteomeXchange, PXD ID: PXD000168. Experiment: BV_2_High_pH_biological_1, file: 20121208_L_4.mzML. Published as part of Proteomics. 2013 Aug 14 . From the Abstract: {{i}} ... A characterization of microglia proteome would facilitate on the study of microglial functions in association with various neurodegenerative diseases. To build a reference proteome, we established a BV-2 microglial proteome to a depth of 5494 unique protein groups using a novel strategy that combined FASP, StageTip-based high pH fractionation, and high-resolution mass spectrometry quickly and cost-efficiently. By bioinformatics analysis, the BV-2 proteome is a valuable resource for studies of microglial function, such as in the immune response, inflammatory response, and phagocytosis ... {{/i}}
创建时间:
2013-09-11
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