Human IDH1 R132C mutant complexed with compound A.
收藏Protein Data Bank Japan2024-03-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6io0
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资源简介：
Human IDH1 R132C mutant complexed with compound A. Descriptor: (2E)-3-{3-[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazole-4-carbonyl]-1-methyl-1H-indol-7-yl}prop-2-enoic acid, CITRIC ACID, GLYCEROL, ... Authors: Suzuki, M, Baba, D, Hanzawa, H. Deposit date: 2018-10-29 Release date: 2019-10-30 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model. Mol.Cancer Ther., 19, 2020
创建时间：
2018-10-29
