Cullin 4B (CUL4B) is a scaffold protein of the CUL4B-Ring E3 ligase (CRL4B) complex. Here, we found that CRL4B interacted with transcriptional corepressor complexes. Our results supporting CUL4B as a

NIAID Data Ecosystem20

Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer.

癌症转录调控

核受体合作机制

Retinoic acid receptor-alpha (RAR alpha) is a known estrogen target gene in breast cancer cells. The consequence of RAR alpha induction by estrogen was previously unknown. We now show that RAR alpha i

NIAID Data Ecosystem30

KEGG pathway and TF enrichment tests for BRCA modules using microarray and RNA-Seq data derived with different algorithms.

癌症转录调控

通路富集分析

“# of enriched modules” indicates the number of modules enriched with at least one KEGG pathway. “Ratio of enriched modules in KEGG” is computed by “# of enriched modules in KEGG” divided by “# of mod

NIAID Data Ecosystem20

Human hepatoma cell lines ChIP-sequencing and RNA-seq

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