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Profiling of bedaquiline (BDQ) induced transcriptome suggests amino acid metabolism and stress responses as alternate mechanisms contributing to BDQ tolerance in Mycobacterium tuberculosis (Mtb).

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP512117
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资源简介:
Whole transcriptome analysis of BDQ resistant Mycobacterium tuberculosis isolates (n=6) and H37Rv after 72 hours of bedaquiline (BDQ) pressure (3.75 &#181g/ml). Exposed isolates were compared to unexposed controls at t= 72 hours to identify genes being differentially regulated due to BDQ stress.
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2025-12-13
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