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Single-cell roadmap of immune cell responses in chronic myeloid leukemia

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NIAID Data Ecosystem2026-05-01 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001005044
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To study the innate and adaptive immune responses in CML, we profiled 25 samples from CML patients including samples at diagnosis (n = 7, N = 9, where n is the number of subjects and N the number of samples if different from n) and before and after TKI-cessation with imatinib (n = 6, N = 15) with paired single-cell RNA and T cell receptor (TCR) αβ chain sequencing (scRNA+TCRαβ-seq) and compared our data to different cancers (n = 29) and healthy donors (n = 7). This dataset contains the samples from before and after TKI-cessation, please see the manuscript for info related to the other datasets.EGA study EGAS00001005044
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2023-11-08
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