five

Rat ex vivo cataract model using DNA damage inducer

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE194317
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By adding MMS or Bleomycin, a DNA damage inducing agent, to the removed rat lens and culturing it, opacity was formed in the lens. To investigate genes whose expression fluctuates when DNA damage is inflicted and causes lens opacity, microarray analysis was performed. Genes whose expression was altered by MMS or Bleomycin compared to the control sample were extracted.
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2023-01-04
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