Supplementary Material for: Minimally Invasive Full-Thickness Resection of a Non-Lifting Adenoma in an Ulcerative Colitis Patient Using OVESCO - A Case Report

Patients with longstanding ulcerative colitis (UC) face an increased risk of colorectal cancer,
necessitating regular surveillance. Chronic inflammation frequently leads to submucosal
fibrosis, making the resection of non-lifting lesions difficult with standard techniques like
endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD).

We present a 76-year-old UC patient with a splenic flexure adenoma that was unresectable
via EMR/ESD. Given the high surgical risk, the OVESCO system was used, achieving clear
margins and avoiding colectomy. This case highlights full-thickness resection devices (FTRD)
as a minimally invasive alternative for challenging polyps in UC, preserving bowel function
while avoiding major surgery or stoma formation.