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RNA Sequencing of db/db mice treated by dapagliflozin

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA851550
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Dapagliflozin, an inhibitor of sodium-glucose cotransporter 2 (SGLT2), is a novel class of oral hypoglycemic drugs that promote glucose excretion in the kidney. Studies have shown that dapagliflozin has renoprotective effect in the treatment of type 2 diabetes. However, the underlying mechanism remains unclear. Here, we used RNA sequencing to explore the molecular mechanism of dapagliflozin in the treatment of diabetic nephropathy (DN).
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2022-06-22
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