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Crystal structure of a topoisomerase ATP inhibitor

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Crystal structure of a topoisomerase ATP inhibitor Descriptor: 6'-[(ethylcarbamoyl)amino]-4'-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-3,3'-bipyridine-5-carboxylic acid, Topoisomerase IV subunit B Authors: Basarab, G.S, Manchester, J.I, Bist, S, Boriack-Sjodin, P.A, Dangel, B, Illingsworth, R, Uria-Nickelsen, M, Sherer, B.A, Sriram, S, Eakin, A.E. Deposit date: 2013-07-14 Release date: 2013-11-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J.Med.Chem., 56, 2013
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2013-07-14
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