Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor Descriptor: N-{3-[1-(3,3-Dimethyl-butyl)-4-hydroxy-2-oxo-1,2,4a,5,6,7-hexahydro-pyrrolo[1,2-b]pyridazin-3-yl]-1,1-dioxo-1,2-dihydro -1lambda6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide, RNA-directed RNA polymerase Authors: Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R. Deposit date: 2008-04-18 Release date: 2009-04-21 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg.Med.Chem.Lett., 18, 2008
创建时间：
2008-04-18
