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Epigenetic profiling of OT-I CD8+ T cells after T cell activation. Epigenetic profiling of OT-I CD8+ T cells after T cell activation

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA940469
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资源简介:
T cells undergo epigenetic changes upon T cell activation. We used the Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq) to analyze epigenetic changes in T cells that were sufficient for or lacked PSGL-1 (gene: Selplg) two hours after T cell activation. Overall design: Naive PSGL-1+/+ or PSGL-1-/- OT-I CD8+ T cells were isolated using magnetic bead separation and activated using immobilized anti-CD3 antibody for 2 hours.
创建时间:
2023-03-02
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