Synthetic Study of Pactamycin: Enantioselective Construction of the Pactamycin Core with Five Contiguous Stereocenters
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https://figshare.com/articles/dataset/Synthetic_Study_of_Pactamycin_Enantioselective_Construction_of_the_Pactamycin_Core_with_Five_Contiguous_Stereocenters/3370597
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A synthetic study of pactamycin is described. Enantioselective construction of the aminocyclopentitol core of pactamycin bearing five contiguous stereocenters was achieved based on an organocatalytic asymmetric aziridination of 2-cyclopentene-1-one, a regio- and diastereoselective 1,3-dipolar cycloaddition, and a rhodium-catalyzed C–H amination reaction.
创建时间:
2016-05-16



