Additional file 1: Table S1. of A database of human genes and a gene network involved in response to tick-borne encephalitis virus infection

Human genes/proteins (51) that had direct physical interactions with TBE viral particle, TBEV proteins or RNA. Table S2. Human genes (76) encoding mRNAs (or proteins) that were up- or down-regulated in response to TBEV infection. Table S3. Human genes (9) that possessed allelic variants associated with susceptibility or resistance to TBEV infection. Table S4. Human genes (6) encoding proteins that were required for inhibitory effect of other proteins against TBEV or attenuated its antiviral activity. Table S5. Human genes (6): knockout of these genes in mice increased mortality rates or effected the other clinical manifestations of the disease. Table S6. All genes from the catalog (140 genes). Table S7. Direct physical interactions (25) that were obtained from STRING and passed manual verification. Table S8. Genes/proteins from the catalog (41) that had one or more pairwise interactions with human genes/proteins within the network. (XLSX 151Â kb)