Related data for this study.

ObjectiveNon-pharmacological intervention represents a significant therapeutic modality for the cognitive function intervention management of patients with type 2 diabetes accompanied by mild cognitive impairment. However, it remains unclear which intervention measure is the most effective. The objective of this study is to compare and rank the influences of various non-pharmacological interventions on the cognitive function of patients with type 2 diabetes and mild cognitive impairment.MethodsEight databases from the establishment of the database to November 2024 were retrieved. The quality of the literature was evaluated using the RoB2.0 tool. Paired Meta-analysis was conducted using Stata/SE 15.1 software, and Network Meta-analysis was performed using R 4.3.1 software.ResultsA total of 25 literatures were incorporated, encompassing 5 intervention measures, with a sample size of 2,446 cases. The results indicated that in the pairwise meta-analysis, when the MoCA score was used as the outcome indicator, cognitive training [MD = 2.3, 95% CI (1.64, 2.96), P MD = 2.11, 95% CI (1.30, 2.92), P MD = 2.28, 95% CI (0.76, 3.81), P MD = 1.98, 95% CI (1.53, 2.48), P MD = 2.03 95% CI (1.57, 2.49), P MD = 2.78, 95% CI (1.48, 4.08), P MD = 2.09, 95% CI (1.46, 2.73), P ConclusionThe current evidence indicates that cognitive training, exercise therapy, and TCM therapy might be relatively effective intervention approaches for improving the cognitive function of patients with type 2 diabetes mellitus (T2DM) accompanied by mild cognitive impairment (MCI), and cognitive training could potentially be the most efficacious non-pharmacological treatment method. Constrained by the quantity and quality of the studies, more high-quality research is still required in the future to further validate this conclusion.