MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage.
收藏ImmuneData2026-05-28 收录
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Two of four MR1-restricted clones were stimulated by the epitope presented by A549 cells. The responsive clones expressed TRBV 4-2 or TRBV 20-1 and the unresponsive clones expressed TRBV 6-4 or TRBV 20-1 and all were responsive to M. smegmatis-infected A549 cells. The authors concluded that MAIT cells can discriminate between MR1-restricted ligands.
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2014-01-01



