ScInfeRDB

ScInfeRDB is an interactive database that provides curated scRNA-seq references and marker sets for 329 cell types across 28 tissue types. It supports accurate cell-type annotation in scRNA-seq, scATAC-seq, and spatial transcriptomics datasets, demonstrating superior performance and robustness against batch effects. ScInfeRDB is publicly available to facilitate seamless cell-type classification.ScInfeRDB 是一款交互式数据库，针对28种组织类型中的329种细胞类型，提供经人工甄选整理的单细胞RNA测序（single-cell RNA sequencing, scRNA-seq）参考数据集与标记基因集。该数据库支持对scRNA-seq、单细胞转座酶可及性测序（single-cell assay for transposase-accessible chromatin using sequencing, scATAC-seq）以及空间转录组学数据集开展精准的细胞类型注释，且在抵御批次效应方面展现出优异的性能与鲁棒性。ScInfeRDB 现已公开可用，以助力实现无缝衔接的细胞类型分类流程。

搜集汇总

背景与挑战

背景概述

ScInfeRDB是一个交互式数据库，提供329种细胞类型和28种组织类型的scRNA-seq参考数据和标记集，用于支持scRNA-seq、scATAC-seq和空间转录组学数据中的细胞类型注释，其性能优越且能有效对抗批次效应。该数据库公开可用，旨在促进无缝的细胞类型分类。