Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 -- Crystal structure of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 in complex with Z48978335 (DNV2_NS5A-x1196)

Protein Data Bank Japan2026-02-18 更新2026-03-21 收录

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Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 -- Crystal structure of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 in complex with Z48978335 (DNV2_NS5A-x1196) Descriptor: 1'H-spiro[cyclopentane-1,2'-quinazolin]-4'(3'H)-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... Authors: Saini, M, Chopra, A, Aschenbrenner, J.C, Marples, P.G, Balcomb, B.H, Fearon, D, von Delft, F, Ruiz, F.X, Arnold, E. Deposit date: 2024-10-15 Release date: 2024-10-30 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 To Be Published

登革病毒2型NS5 RNA依赖的RNA聚合酶（RNA-dependent RNA polymerase）晶体学片段筛选集体提交 —— 登革病毒2型NS5 RNA依赖的RNA聚合酶与Z48978335结合的晶体结构（编号：DNV2_NS5A-x1196）描述符：1'H-螺[环戊烷-1,2'-喹唑啉]-4'(3'H)-酮、2-(N-吗啉代)乙磺酸、二(羟乙基)醚…… 作者：Saini, M、Chopra, A、Aschenbrenner, J.C、Marples, P.G、Balcomb, B.H、Fearon, D、von Delft, F、Ruiz, F.X、Arnold, E 提交日期：2024-10-15 发布日期：2024-10-30 最后修改日期：2026-02-18 实验方法：X射线衍射（分辨率1.66 Å）引用说明：登革病毒2型NS5 RNA依赖的RNA聚合酶晶体学片段筛选集体提交待发表

创建时间：

2024-10-15