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RNA-seq analysis of WT and NCOR1f/f,Cd4Cre in vitro-generated Th17 cells

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP225858
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资源简介:
The differentiation of naïve CD4+ T cells into T helper (Th) subsets is key for a functional immune response and has to be tightly controlled by transcriptional and epigenetic processes. However, the function of cofactors that connect gene-specific transcription factors with repressive chromatin-modifying enzymes in Th cells is yet unknown. Here we determined transcriptional changes in Th17 cells upon deletion of the cofactor NCOR1. Overall design: mRNA expression profiles of WT and NCOR1f/f,Cd4Cre in vitro-generated Th17 cells were generated by deep sequencing
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2020-04-28
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