Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/-sterol (DOPC, DOPE, DOPS, PI(4,5)P2 50:20:20:10)
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Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/-sterol (DOPC, DOPE, DOPS, PI(4,5)P2 50:20:20:10) Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Sphingolipid long chain base-responsive protein PIL1 Authors: Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. Deposit date: 2023-08-24 Release date: 2024-07-24 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (3.86 Å) Cite: Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain. Nature, 632, 2024
酵母胞膜凹陷小体(eisosome)蛋白Pil1的螺旋重构:该蛋白结合于由脂质混合物构成的膜,脂质混合物含PIP2且不含固醇,具体组成为DOPC、DOPE、DOPS、PI(4,5)P2,摩尔比为50:20:20:10。描述符:D-肌醇-1,4,5-三磷酸、鞘脂长链碱基响应蛋白PIL1。作者:Kefauver, J.M.、Zou, L.、Desfosses, A.、Loewith, R.J.。存档日期:2023年8月24日。发布日期:2024年7月24日。最后修改日期:2024年8月28日。实验方法:冷冻电子显微镜(分辨率3.86埃)。引用文献:《近天然牵张敏感膜微域的冷冻电镜结构》,《自然》(Nature),第632卷,2024年。



