IGF2BP3 increases IL-13/IL-4 signalling in human bronchial epithelial cell

To investigate the genome-wide role of RNA binding protein IGF2BP3 in IL13 mechanisms of action in bronchial epithelial cells Overall design: Constitutive knock down shControl and shIGF2BP3 BEAS-2B ce

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Human airway epithelial cells co-treated with IL-4 and IL-13 for seven days.. Human airway epithelial cells co-treated with IL-4 and IL-13 for seven days.

Nasal basal epithelial cells from 6 healthy adult donors were grown in air-liquid interface (ALI) cultures for fourteen days. Cells were then treated with 10 ng/mL of IL-4 and 10 ng/mL of IL-13 for se

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IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms. IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms

Myelofibrosis (MF) is a disease with high unmet medical need since bone marrow transplant is not an option for many patients and JAK inhibitors are generally effective for only 2-3 years. MF is charac

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