BindingDB Entry 50039744: Structure-based design of novel class II c-Met inhibitors: 2. SAR and kinase selectivity profiles of the pyrazolone series.

Small molecule binding data for protein AKT/p21CIP1, Aurora kinase B/Inner centromere protein, Cyclin-Dependent Kinase 5 (CDK5), Fibroblast growth factor receptor 1, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, JAK3/JAK1, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Macrophage-stimulating protein receptor, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 3, Mitogen-activated protein kinase 9, Ribosomal protein S6 kinase (P70S6K), Ribosomal protein S6 kinase alpha 5, SRC, Serine/threonine-protein kinase AKT, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase PIM, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BTK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), and cAMP-dependent protein kinase (PKA), Uniprot O14965, O60674, O75582, P00519, P06213, P06239, P07949, P08069, P08581, P10721, P11309, P11362, P12931, P17612, P23443, P23458, P27361, P31749, P31751, P35968, P45984, P52333, Q00535, Q02763, Q04912, Q06187, Q15078, Q16539, Q96GD4, and Q9P1W9