Neutral and Ionic Cycloruthenated 2‑Phenylindoles as Cytotoxic Agents
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https://figshare.com/articles/dataset/Neutral_and_Ionic_Cycloruthenated_2_Phenylindoles_as_Cytotoxic_Agents/2339293
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资源简介：
The synthesis and characterization
of two families of cyclometalated
Ru(II) complexes with the new (Csp2,Nindole)− motif formed by activation of the C–H
bonds of 2-phenylindole ligands of the general formula {(4′-R1-C6H4)-3-NOMe-5-R2-6-R3-(C6H2N)} are presented. The novel ruthenacycles
show a remarkable cytotoxic activity in MCF7 and MDA-MB231 breast
cancer cell lines, which clearly exceeds those of the trans and cis isomers of [PtCl2(L)(DMSO)]
derived from the same ligands and even that of cisplatin.
创建时间：
2016-02-18
