Discovery POE association results for the six SNPs selected for replication.

SNP matching any of the following two selection criteria were retained: (1) All lead SNPs with POE P-value below 5×10−6. (2) All lead SNPs falling in previously reported imprinted regions with POE P-value <5×10−4. Note that one SNP is listed twice as it met both criteria. Chr: chromosome, Gene: nearest gene, MAF: minor allele frequency, N (AA+BB): homozygous sample size, N (AB): heterozygous sample size, P-value (main): main effect association P-value in Speliotes et al. [10]. The parent of origin P-value, “P-value (POE)”, is the Brown-Forsythe test P-value. SNPs marked in bold are those which replicated in the family studies, see Table 2.