Acquired resistance to combination dabrafenib/trametinib therapy in BRAF mutant metastatic melanoma
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https://www.ncbi.nlm.nih.gov/sra/ERP007240
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资源简介:
One third of BRAF-mutant metastatic melanoma patients treated with combined BRAF and MEK inhibition progress within six months. Treatment options for these patients remain limited. We sequenced the exomes of eight matched pre-treatment and progressing melanoma pairs using Illumina Exome TrueSeq. The tumors were derived from 8 BRAFV600 mutant melanoma patients treated with combination dabrafenib and trametinib.
创建时间:
2021-02-04



