Palladium-Catalyzed Regio‑, Diastereo‑, and Enantioselective Allylation of Nitroalkanes with Monosubstituted Allylic Substrates

Pd-catalyzed asymmetric allylic alkylation of nitroalkanes and monosubstituted allylic substrates was performed to afford products with two adjacent chiral centers and with excellent regio-, diastereo-, and enantioselectivities. The usefulness of the protocol in organic synthesis was demonstrated by transformation of the product to an optically active homoallyl­amine, a 2,3-disubstituted tetrahydro­pyridine, and an α,β-disubstituted amino acid derivative.