Diagnostic accuracy of point shear wave elastography and transient elastography for staging hepatic fibrosis in patients with non-alcoholic fatty liver disease: a meta-analysis

Objective: This study aimed to assess the accuracy of staging liver fibrosis in Non-Alcoholic Fatty Liver Disease Patients (NAFLD) via Point shear wave Elastography (pSWE) and Transient Elastography (TE).
Setting: Relevant records concerning NAFLD were retrieved from Pubmed, Embase, Web of Science, and the China National Knowledge Infrastructure databases up to 20th of December, 2017. A bivariate mixed-effects model was conducted to combine sensitivity (SE), specificity (SP), positive likelihood ratio (LR+), negative likelihood ratio (LR-) and Area Under Summary Receiver Operating Characteristic Curve (AUC) between TE and pSWE. A sensitivity analysis was implemented to explore the source of heterogeneity.
Participants: Patients with NAFLD who had a liver stiffness measurement using pSWE and TE before liver biopsy were enrolled according to the following criteria : 2×2 contingency tables can be calculated via the reported numbers of cases, sensitivity and specificity and were exclude...