Effect of Cyclohexidmide treatment on early transcription of HSV-1 ΔICP22 and repaired virus
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213098
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Study was performed to assess the requirement for HSV-1 IE protein, ICP22, to be expressed to regulate early HSV-1 transcription PRO-Seq was performed on nuclei extracted at 1.5 hpi from HEp-2 cells infected with ΔICP22 HSV-1 mutant and its genetically restored repair. Infections occurred at an MOI of 5 in the presence or absence of the protein synthesis inhibitor cycloheximide (CHX)
创建时间:
2023-01-17



