DataSheet1_Early screening tool for developmental delay in infancy: Quantified assessment of movement asymmetry using IR-UWB radar.docx

In the untact COVID-19 era, the feasibility of a noncontact, impulse-radio ultrawideband (IR-UWB) radar sensor has important medical implications. Premature birth is a major risk factor for brain injury and developmental delay; therefore, early intervention is crucial for potentially achieving better developmental outcomes. Early detection and screening tests in infancy are limited to the quantification of differences between normal and spastic movements. This study investigated the quantified asymmetry in the general movements of an infant with hydrocephalus and proposes IR-UWB radar as a novel, early screening tool for developmental delay. To support this state-of-the-art technology, data from actigraphy and video camcorder recordings were adopted simultaneously to compare relevant time series as the infant grew. The data from the three different methods were highly concordant; specifically, the ρz values comparing radar and actigraphy, which served as the reference for measuring movements, showed excellent agreement, with values of 0.66 on the left and 0.56 on the right. The total amount of movement measured by radar over time increased overall; movements were almost dominant on the left at first (75.2% of total movements), but following shunt surgery, the frequency of movement on both sides was similar (54.8% of total movements). As the hydrocephalus improved, the lateralization of movement on radar began to coincide with the clinical features. These results support the important complementary role of this radar system in predicting motor disorders very early in life.

在无接触的COVID-19时代，非接触式脉冲无线电超宽带（IR-UWB）雷达传感器的可行性具有重要的医学意义。早产是脑损伤和发育迟缓的主要风险因素，因此，早期干预对于可能实现更好的发育结果至关重要。婴儿早期检测和筛查测试仅限于正常运动与痉挛运动之间的差异量化。本研究调查了脑积水婴儿总体运动中的量化不对称性，并提议将IR-UWB雷达作为一种新型、早期筛查发育迟缓的工具。为了支持这一前沿技术，同时采用了动作追踪器和视频摄像机的数据记录，以比较随着婴儿成长的相关时间序列。三种不同方法的数据高度一致；具体而言，用于测量运动的雷达与动作追踪器之间的ρz值，作为测量运动的参考，表现出优异的一致性，左侧值为0.66，右侧值为0.56。雷达随时间测量的总运动量总体上有所增加；最初，运动几乎在左侧占主导地位（占总运动的75.2%），但随后分流手术之后，两侧的运动频率相似（占总运动的54.8%）。随着脑积水的改善，雷达上的运动侧化开始与临床特征相一致。这些结果支持了该雷达系统在预测生命早期运动障碍中的重要作用。