Tankyrase 1 with Phthalazinone 1
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5ece
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资源简介：
Tankyrase 1 with Phthalazinone 1 Descriptor: 1,2-ETHANEDIOL, 2-[4-[3-[(4-oxidanylidene-3~{H}-phthalazin-1-yl)methyl]phenyl]carbonylpiperazin-1-yl]pyridine-3-carbonitrile, ACETATE ION, ... Authors: Kazmirski, S.L, Johannes, J, Read, J.A, Howard, T, Larsen, N.A, Ferguson, A.D. Deposit date: 2015-10-20 Release date: 2015-11-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering. Bioorg.Med.Chem.Lett., 25, 2015
创建时间：
2015-10-20
