Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911
收藏Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911 Descriptor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({2-[(1-cyclopentylpiperidin-4-yl)amino]-1,3-benzothiazol-6-yl}sulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-p henylbutan-2-yl}carbamate, HIV-1 protease, PHOSPHATE ION Authors: Schiffer, C.A, Nalam, M.N.L. Deposit date: 2011-03-17 Release date: 2011-09-21 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: TMC310911, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor, Shows In Vitro an Improved Resistance Profile and Higher Genetic Barrier to Resistance Compared with Current Protease Inhibitors. Antimicrob.Agents Chemother., 55, 2011
创建时间：
2011-03-17
