Evaluation of the CF-GA method.

Best quality conformation found in the top 10 ranked solutions from target 22 to target 40 for genetic algorithm (GA), collaborative filtering (CF) and combination of the previous two (CF-GA) methods, with RMSD filtering. Same results are given for the CF-GA method without RMSD filtering, and for the CF then GA method. N: Numbers of acceptable or better solutions in the top 10; R: rank of the first acceptable or better solution for each target. Numbers of high quality (), medium quality (), acceptable () and incorrect conformations in each ensemble and for each method when using RMSD filtering are given in Table 4.