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Structure of the kinase domain of c-Met bound to XL880 (GSK1363089)

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Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Structure of the kinase domain of c-Met bound to XL880 (GSK1363089) Descriptor: Hepatocyte growth factor receptor, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide Authors: Lougheed, J.C, Stout, T.J. Deposit date: 2010-02-08 Release date: 2010-05-19 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases. Cancer Res., 69, 2009
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2010-02-08
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