Arginine-dependent gene regulation in Streptococcus gordonii ahrC regulator knockout. Streptococcus gordonii str. Challis

We have previously shown that responses of the oral bacterium Streptococcus gordonii to arginine are co-ordinated by three paralogous regulators: ArcR, ArgR and AhrC. This set of experiments was designed to assess the effects of the AhrC gene regulator on global gene expression in Streptococcus gordonii under high arginine or following a shift to no arginine. Overall design: Single colour microarrays were used to measure gene expression in four biological replicates of S. gordonii cells cultured, with and without arginine restriction. One replicate of 'arg+' was identified as an outlier and was not processed for normalised data. The raw data text file for this data set (US92200305_254184610003_S01_GE1_107_Sep09_1_2.txt) has been included in the supplementary files.