Data from Uniaxial Compression testing and validation scripts for Cauchy stress modeling to design anatomical silicone replicas

Anatomically realistic organ replicas or phantoms allow for accurate studies and reproducible research. To recreate a human kidney, mimicry of the viscoelastic properties of the human kidney is crucial. However, none of the related work addressed the design and development of a kidney phantom using only silicone as material. In contrast to paraffin and hydrogel, silicone is an ideal variant for its extended shelf life, soft-tissue-like feeling, and viscoelastic modularity. To this end, we conducted uniaxial compression testing and Cauchy stress modeling. Results indicate that none of the available manufacturer silicone brands are suitable for the task of creating a realistic kidney phantom. Indeed, the tested silicone mixtures in low and high strain do not fall within the required approximate target compressive moduli of 20 kPa and 500 kPa, respectively. This work provides a frame of reference for future work by avoiding the pitfalls of the selected ready-made silicones and reusing the reported theoretical and experimental setup to design a realistic replica of the kidney organ.

解剖学上逼真的器官复制品或幻影，能够实现对研究的精确探讨及研究的可重复性。为了重现人类肾脏，模拟人类肾脏的粘弹性质至关重要。然而，现有的相关研究并未涉及仅使用硅胶作为材料设计和发展肾脏幻影的设计与开发。与石蜡和亲水凝胶相比，硅胶因其较长的保质期、类似于软组织的触感和粘弹性能的多样性，成为理想的替代品。为此，我们进行了单轴压缩测试和柯西应力建模。结果表明，现有的制造商硅胶品牌均不适合创建逼真的肾脏幻影。事实上，在低应力和高应力下测试的硅胶混合物，其所需的近似目标压缩模量（分别为20 kPa和500 kPa）均未达到。本研究为未来的研究提供了参考框架，通过避免选择现成硅胶的潜在缺陷，并重用所报道的理论和实验设置，来设计逼真的肾脏器官复制品。