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ena-DATASET-DKFZ-IBIOS-29-08-2014-08:27:40:831-1015 - samples

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https://www.omicsdi.org/dataset/ega/EGAD00001000997
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资源简介:
Whole-exome sequencing of a chronic lymphocytic leukemia (CLL) developed during vemurafenib treatment of a patient with malignant melanoma. Peripheral blood mononuclear cells were separated by Ficoll gradient centrifugation. DNA was extracted from highly purified (>97%) CD19+CD5+ cells obtained from the patient while being under BRAF inhibition versus CD14+ germline control cells (>90% purity). No alterations that could be linked to aberrant RAS activity or paradoxical RAF/MEK/ERK signaling could be identified in the CLL, which shows characteristic copy number alterations.EGA dataset EGAD00001000997
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2017-07-26
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