Effect of glucose on the number of living beta cells.

Adult rat (8-week-old) beta cells were cultured in serum-free medium at the indicated concentrations of glucose. The numbers of viable beta cells are expressed as absolute cell number per well and as percent of the numbers on day 1. Data represent means ± SEM; compared with day 1 values: *, p<0.05; **, p<0.01; ***, p<0.001; compared with 10 mmol/l glucose condition on day 15: ≠, p<0.001; #, p<0.01; n = 8.