WP4536 - Genes related to primary cilium development (based on CRISPR) - Homo sapiens

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The primary cilium is related Hedgehog signaling, embryonic and brain[https://www.ncbi.nlm.nih.gov/pubmed/29030052] development. When it is disregulated, it leads to ciliopathies[https://www.ncbi.nlm.nih.gov/pubmed/21210154]. The genes in this pathway are related to several ciliary structures, which have been discovered with genome-wide CRISPR-mediated gene disruption.

创建时间：

2025-04-17