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Crystal structure of the bromodomain of human CREBBP in complex with a benzoxazepine compound

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Crystal structure of the bromodomain of human CREBBP in complex with a benzoxazepine compound Descriptor: 1,2-ETHANEDIOL, 7-(3,5-dimethoxyphenyl)-N-[(3S)-1-methylpiperidin-3-yl]-4-propanoyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, CREB-binding protein Authors: Tallant, C, Popp, T.A, Fedorov, O, Siejka, P, Picaud, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bracher, F, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2016-03-28 Release date: 2016-10-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.05 Å) Cite: Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors. J.Med.Chem., 59, 2016
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2016-03-28
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