Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-benzylpiperazin-1-yl)methyl]-6-(2-chloro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid

Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-benzylpiperazin-1-yl)methyl]-6-(2-chloro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid Descriptor: (5M)-2-[(4-benzylpiperazin-1-yl)methyl]-5-(2-chloro-4-methylphenyl)-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published

人环状GMP-AMP合酶（cyclic GMP-AMP synthase）与2-[(4-苄基哌嗪-1-基)甲基]-6-(2-氯-4-甲基苯基)-1H-苯并咪唑-4-羧酸的复合物晶体结构。配体描述：(5M)-2-[(4-苄基哌嗪-1-基)甲基]-5-(2-氯-4-甲基苯基)-1H-苯并咪唑-7-羧酸、环状GMP-AMP合酶、锌离子（ZINC ION）。作者：Leibrock, L、Benz, J、Groebke-Zbinden, K、Galley, G、Rudolph, M.G.。沉积日期：2023-02-08。发布日期：2024-02-21。末次修改日期：2026-02-18。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.06埃（Å）。引用文献：《人环状GMP-AMP合酶复合物晶体结构》，待发表。