Effect of copper nanoparticles in the diet of WKY and SHR rats on the redox profile and histology of the heart, liver, kidney, and small intestine

Blood biochemical parameters, redox status in heart, liver, kidney, and small intestinal tissue. Data were obtained during an in vivo experiment on rats. Normotensive male Wistar–Kyoto rats (WKY) were allocated to three groups. Three analogous groups of spontaneously hypertensive rats (SHR) were also formed. The WKY and SHR rats received copper in a standard daily dose—6.5 mg/kg CuCO3 or CuNPs (100% replacement) or 3.25 mg/kg CuCO3 plus 3.25 mg/kg CuNPs (50% replacement)—for 8 weeks.