Insights into structural integration of the PLCgamma regulatory region and mechanism of autoinhibition and activation based on key roles of SH2 domains
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Insights into structural integration of the PLCgamma regulatory region and mechanism of autoinhibition and activation based on key roles of SH2 domains Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Authors: Cole, A.R, Mas-Droux, C.P, Bunney, T.D, Katan, M. Deposit date: 2012-05-23 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural and Functional Integration of the PLCgamma Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation. Structure, 20, 2012
基于SH2结构域(SH2 domain)关键作用的PLCgamma(PLCγ1)调控区域结构整合及自抑制与激活机制研究洞察 描述符:1-磷脂酰肌醇4,5-二磷酸磷酸二酯酶γ1 作者:科尔(Cole, A.R.)、马-德鲁克斯(Mas-Droux, C.P.)、邦尼(Bunney, T.D.)、卡坦(Katan, M.) 提交日期:2012年5月23日 发布日期:2012年10月31日 最后修改日期:2024年2月28日 研究方法:X射线衍射(X-RAY DIFFRACTION,分辨率2.4埃) 引用文献:《调控机制与信号失调关键相关的PLCgamma相互作用结构域的结构与功能整合》,《Structure》,第20卷,2012年



