The Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state Kinetics and X- Ray Crystallography of Correct and Incorrect Pairing

The Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state Kinetics and X- Ray Crystallography of Correct and Incorrect Pairing Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*T)-3', 5'-D(*TP*CP*AP*C BZGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... Authors: Eoff, R.L, Angel, K.C, Kosekov, I.D, Egli, M, Guengerich, F.P. Deposit date: 2007-01-17 Release date: 2007-03-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing. J.Biol.Chem., 282, 2007

嗜热硫化叶菌（Sulfolobus solfataricus）DNA聚合酶IV（DNA Polymerase IV）介导三磷酸核苷（nucleoside triphosphate）掺入O6-苄基鸟嘌呤（O6-Benzylguanine）对位的选择性分子基础：正确与错误配对的稳态动力学（steady-state kinetics）、预稳态动力学（pre-steady-state kinetics）与X射线晶体学（X-Ray Crystallography）
描述符：2'-脱氧鸟苷-5'-三磷酸（2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE）、5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*T)-3'、5'-D(*TP*CP*AP*C BZGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3'……
作者：Eoff, R.L.、Angel, K.C.、Kosekov, I.D.、Egli, M.、Guengerich, F.P.
提交日期：2007-01-17
发布日期：2007-03-13
最后修改日期：2023-12-13
实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.39埃）
引用文献：嗜热硫化叶菌DNA聚合酶Dpo4介导三磷酸核苷掺入O6-苄基鸟嘌呤对位的选择性分子基础：正确与错误配对的稳态与预稳态动力学及X射线晶体学。《生物化学杂志》（J.Biol.Chem.），282卷，2007年